The glycosynapse
نویسندگان
چکیده
MICROBIOLOGY. For the article ‘‘Subcellular localization of acetylCoA carboxylase in the apicomplexan parasite Toxoplasma gondii,’’ by J. Jelenska, M. J. Crawford, O. S. Harb, E. Zuther, R. Haselkorn, D. S. Roos, and P. Gornicki, which appeared in number 5, February 27, 2001, of Proc. Natl. Acad. Sci. USA (98, 2723–2728; First Published February 13, 2001; 10.1073 pnas.051629998), the authors note that the acknowledgments should read: ‘‘This project was supported by a gift from Monsanto, a grant from Merck Co., and a grant from the Rockefeller Foundation.’’
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Glycosynapses: microdomains controlling carbohydrate-dependent cell adhesion and signaling.
The concept of microdomains in plasma membranes was developed over two decades, following observation of polarity of membrane based on clustering of specific membrane components. Microdomains involved in carbohydrate-dependent cell adhesion with concurrent signal transduction that affect cellular phenotype are termed "glycosynapse". Three types of glycosynapse have been distinguished: "type 1" ...
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